Monday, August 4 2008
So That's What It Looks Like
Cartoon view of a crystal structure (PDB-1LDY)
of Liver Alcohol Dehydrogenase showing the system consists
of two dimers in close proximity when crystallised.
Illo from Ross Walker
Liver Alcohol Dehydrogenase converts alcohol into acetaldehyde in your bloodstream, the first step to breaking down blood alcohol. The next? Acetaldehyde Dehydrogenase, of course!
Further interesting aspects of the stokes shift of the NADH coenzyme of liver alcohol dehydrogenase and insight into hydride transfer within this system can be found here: Calculations of Optical Spectra of LADH via Application of Linear Response Theory.
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